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Tamoxifen improves coronary arteries in men
March 22, 2001

In the latest issue of Circulation, investigators report that  tamoxifen - a drug used to combat breast cancer in women -  improved blood flow in the coronary arteries of men with heart disease.  The drug also reduced men's cholesterol and triglyceride levels.

The drug was given to 16 of 31 men with coronary artery disease, and results were compared to the 15 who did not receive tamoxifen.  Those who received tamoxifen showed a significant increase in blood flow through the coronary arteries, as well as reductions in cholesterol and triglyceride levels.

The results of this small study are promising, and will lead to larger trials testing whether tamoxifen may be clinically useful in men with coronary artery disease.

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